Peer-reviewed articles

Cerqueira SA, Tan M, Li S, Juillard F, McVey CE, Kaye KM, Simas JP.

LANA E3 Ubiquitin-Ligase Activity Impacts Gammaherpesvirus-Driven Germinal Center B Cell Proliferation. J Virol. 2016 Jun 15. pii: JVI.00813-16. [Epub ahead of print] PubMed PMID: 27307564.

Campos EJ, McVey CE, Astier Y.

Stochastic Detection of MPSA-Gold Nanoparticles Using a α-Hemolysin Nanopore Equipped with a Noncovalent Molecular Adaptor. Anal Chem. 2016 Jun 21;88(12):6214-22. doi: 10.1021/acs.analchem.5b03558. Epub 2016Jun 8. PubMed PMID: 27238076.

Rajesh Ponnusamy, Maxim V. Petoukhov, Bruno Correia,Tania F. Custodio, Franceline Juillard, Min Tan, Marta Pires de Miranda, Maria A. Carrondo, J. Pedro Simas, Kenneth M. Kaye, Dmitri I. Svergun and Colin E. McVey,*
KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA. Nucleic Acids Res. 2015 Sep 30. pii: gkv987.

Shijun Li, Min Tan, Franceline Juillard, Rajesh Ponnusamy, Bruno Correia, J Pedro Simas, Maria A. Carrondo, Colin E. McVey, Kenneth M. Kaye.
The Kaposi's sarcoma herpesvirus latency-associated nuclear antigen DNA binding domain dorsal positive electrostatic patch facilitates DNA replication and episome persistence. J Biol Chem. 2015 Sep 29. pii: jbc.M115.674622.

Elisa Campos, Colin E. McVey, Randy P Carney, Francesco Stellacci, Yann Astier, and James Yates
Sensing Single Mixed-Monolayer Protected Gold Nanoparticles by the α-Hemolysin Nanopore. Analytical Chemistry Just Accepted Publication Date (Web): September 23, 2013 (Article) DOI: 10.1021/ac4014836.

Bruno Correia, Sofia A. Cerqueira, Chantal Beauchemin, Marta Pires de Miranda, Shijun Li, Rajesh Ponnusamy, Lénia Rodrigues, Thomas R. Schneider, Maria A. Carrondo, Kenneth M. Kaye, J. Pedro Simas and Colin E. McVey .
Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency. PLoS Pathogens 2013, 9(10): e1003673. doi:10.1371/journal.ppat.1003673 (online or pdf).

Marta Pires de Miranda, Filipa B. Lopes, Colin E. McVey, Xosé R. Bustelo,and J. Pedro Simas.
Role of Src-homology domain binding in signaling complexes assembled by the murid gammaherpesvirus M2 protein. J. Biol. Chem. 2013 vol. 288 (6) p. 3858-3870.

Elisa Campos, Alina Asandei, Colin E. McVey, João C. Dias, A. Sofia F. Oliveira, Cláudio M. Soares , Tudor Luchian, and Yann Astier. The Role of Lys147 in the Interaction between MPSA-Gold Nanoparticles and the α-Hemolysin Nanopore. Langmuir. 2012 Nov 6;28(44):15643-50.

Gorynia, S., T.M. Bandeiras, F.G. Pinho, C.E. McVey, C. Vonrhein, A. Round, D.I. Svergun, P. Donner, P.M. Matias, and M.A. Carrondo, Structural and Functional Insights into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex. J Struct Biol, Volume 176, Issue 3, December 2011, Pages 279-291.

de Sanctis, D., C.E. McVey, F.J. Enguita, and M.A. Carrondo, Crystal Structure of the Full-Length Sorbitol Operon Regulator Sorc from Klebsiella Pneumoniae: Structural Evidence for a Novel Transcriptional Regulation Mechanism. J Mol Biol, 2009. 387(3): p. 759-70.

de Sanctis, D., A.T. Rego, D. Marcal, C.E. McVey, M.A. Carrondo, and F.J. Enguita, Overexpression, Purification and Crystallization of the Tetrameric Form of Sorc Sorbitol Operon Regulator. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008. 64(Pt 1): p. 22-4.

Cooray, S., M.W. Bahar, N.G. Abrescia, C.E. McVey, N.W. Bartlett, R.A. Chen, D.I. Stuart, J.M. Grimes, and G.L. Smith, Functional and Structural Studies of the Vaccinia Virus Virulence Factor N1 Reveal a Bcl-2-Like Anti-Apoptotic Protein. J Gen Virol, 2007. 88(Pt 6): p. 1656-66.

Frazao, C.*, C.E. McVey*, M. Amblar, A*. Barbas, C. Vonrhein, C.M. Arraiano, and M.A. Carrondo, Unravelling the Dynamics of RNA Degradation by Ribonuclease II and its RNA-Bound Complex. Nature, 2006. 443(7107): p. 110-4. *Contributed Equally

McVey, C.E., M. Amblar, A. Barbas, F. Cairrao, R. Coelho, C. Romao, C.M. Arraiano, M.A. Carrondo, and C. Frazao, Expression, Purification, Crystallization and Preliminary Diffraction Data Characterization of Escherichia coli Ribonuclease II (RNase II). Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006. 62(Pt 7): p. 684-7.

Bartlett, N.W., L. Dumoutier, J.C. Renauld, S.V. Kotenko, C.E. McVey, H.J. Lee, and G.L. Smith, A New Member of the Interleukin 10-Related Cytokine Family Encoded by a Poxvirus. J Gen Virol, 2004. 85(Pt 6): p. 1401-12.

Morillas, M.*, C.E. McVey*, J.A. Brannigan, A.G. Ladurner, L.J. Forney, and R. Virden, Mutations of Penicillin Acylase Residue B71 Extend Substrate Specificity by Decreasing Steric Constraints for Substrate Binding. Biochem J, 2003. 371(Pt 1): p. 143-50. * Contributed Equally

McVey, C.E., M.A. Walsh, G.G. Dodson, K.S. Wilson, and J.A. Brannigan, Crystal Structures of Penicillin Acylase Enzyme-Substrate Complexes: Structural Insights into the Catalytic Mechanism. J Mol Biol, 2001. 313(1): p. 139-50.

Brannigan, J., G. Dodson, S. Done, L. Hewitt, C. McVey, and K. Wilson, Structural Studies of Penicillin Acylase. Applied Biochemistry and Biotechnology, 2000. 88(1): p. 313-319.

Suresh, C.G., A.V. Pundle, H. SivaRaman, K.N. Rao, J.A. Brannigan, C.E. McVey, C.S. Verma, Z. Dauter, E.J. Dodson, and G.G. Dodson, Penicillin V Acylase Crystal Structure Reveals New Ntn-Hydrolase Family Members. Nat Struct Biol, 1999. 6(5): p. 414-6.

McVey, C.E., S.P. Tolley, S.H. Done, J.A. Brannigan, and K.S. Wilson, A New Crystal Form of Penicillin Acylase from Escherichia Coli. Acta Crystallogr D Biol Crystallogr, 1997. 53(Pt 6): p. 777-9.

Book Chapters

S. Gorynia, T.M. Bandeiras, P.M. Matias, F.G. Pinho, C. E. McVey, P. Donner and M.A. Carrondo. “RuvBL1 and RuvBL2 and their complex proteins implicated in many cellular pathways”, in Macromolecular Crystallography: Deciphering the structure, function and dynamics of biological molecules (2012), (M.A Carrondo and P. Spadon, eds) NATOScience for Peace and Security Series A: Chemistry and Biology,pp. 55-63. DOI:10.1007/978-94-007-2530-0_5.

Frazão, C., McVey, C.E., and Carrondo, M.A. (2007). Determinação da Estrutura da Ribonuclease II: uma enzima importante no controlo da expressão génica. In "Annualia" (J. Colaço, Ed.). Editorial Verbo, Lisboa.

Brannigan, J., Ladurner, A., McVey, C. and Forney, L. (1995) Altered specificity mutants of penicillin acylase. In Perspectives on Protein Engineering (Geisow, M., Epton, R., ed.), pp. 124-126, Mayflower Worldwide Ltd