Recent Publications

MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res. 2021 Dec 16;49(22):12895-12911. doi: 10.1093/nar/gkab1094.

In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4. J Virol. 2018 Oct 12;92(21):e01251-18. doi: 10.1128/JVI.01251-18.

Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA. PLoS Pathog. 2017 Sep 14;13(9):e1006555. doi: 10.1371/journal.ppat.1006555.

Latency-Associated Nuclear Antigen E3 Ubiquitin-Ligase Activity Impacts Gammaherpesvirus-Driven Germinal Center B Cell
Proliferation. J Virol. 2016 Jun 15. pii: JVI.00813-16. [Epub ahead of print]PubMed PMID: 27307564.

Stochastic Detection of MPSA-Gold Nanoparticles Using a α-Hemolysin Nanopore Equipped with a Noncovalent Molecular Adaptor. Anal
Chem. 2016 Jun 21;88(12):6214-22. doi: 10.1021/acs.analchem.5b03558. Epub 2016 Jun 8. PubMed PMID: 27238076.

KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA. Nucleic Acids Res. 2015 Sep 30. pii: gkv987. [Epub ahead of print].

The Kaposi's sarcoma herpesvirus latency-associated nuclear antigen DNA binding domain dorsal positive electrostatic patch facilitates DNA replication and episome persistence. J Biol Chem. 2015 Sep 29. pii: jbc.M115.674622.

Sensing Single Mixed-Monolayer Protected Gold Nanoparticles by the α-Hemolysin Nanopore. Analytical Chemistry September 23, 2013 DOI: 10.1021/ac4014836.

Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency. PLoS Pathogens 2013, 9(10): e1003673. doi:10.1371/journal.ppat.1003673 (online or pdf).

Role of Src-homology domain binding in signaling complexes assembled by the murid gammaherpesvirus M2 protein. J. Biol. Chem. 2013 vol. 288 (6) p. 3858-3870.

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